Kratom Lords

What Happens When You Take Kratom Every Morning? (Study) Introduction Kratom, a botanical derived from the leaves of Mitragyna speciosa, has gained popularity in the United States as an alternative remedy. Despite its widespread use, scientific understanding of its effects is limited, primarily relying on retrospective self-report studies. To bridge this gap, a direct-observation study was conducted to assess the acute effects of a typical morning dose of kratom in individuals who use it regularly. Methods Ten adults, regular kratom users, participated in the study, self-administering their typical morning dose without blinding procedures. Physiological measures, subjective outcomes, and psychomotor performance were assessed at various time points. Alkaloids in the kratom products, urine, and plasma were quantified to understand their impact. Results The study included six men and four women with an average age of 41.2 years. Participants had been using kratom for an av...

 G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder Background and Purpose Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self-medication and may be less dangerous than typical opioids because of the stronger preference of kratom alkaloids to induce receptor interaction with G proteins over β-arrestin proteins. The study hypothesizes that kratom (alkaloids) can also reduce alcohol intake. #science #research #kratomresearch #kratomstudy #alkaloids #proteins https://kratomlords.com/kratom-research/protein-biased-kratom-alkaloids-potential-treatments/ G Protein-biased kratom-alkaloids as potential treatments Abstract Background and Purpose Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self-medic...