Posts

Showing posts with the label kratomscience

Kratom Science: Latest Evidence on Safety and Regulation

Image
Kratom Science Update: Evidence-Based Facts The FDA has a long-standing bias against any dietary ingredient, botanical supplement, or dietary supplement that is not a chemical formulation subject to regulatory approval as a new drug. In 1994, Congress passed the Dietary Supplement Health and Education Act (DHEA) to reign in the FDA’s overregulation of dietary supplements FDA wanted banned on the premise they were highly addictive, being used to self-medicate without physician supervision, or were so poorly formulated these products posed a threat to public health requiring them to be banned. What is clearly needed is balanced regulation to ensure that kratom products purchased by consumers are pure and unadulterated, in other words meeting the same types of standards that apply to other food products, and even bottled water. Steps toward such standards were taken in states that passed their own versions of kratom consumer protection act laws. Ultimately, the Food and Drug Administratio...

5 Tips to choose the best red maeng da kratom vendor

Image
  Red Maeng Da Kratom is arguably one of  the best Kratom strains  and has a significant online presence. However, many people do not know the exact benefits of this plant-based product. Maeng da Kratom strains are highly beneficial in pain relief, mood elevation, energy boosting, etc. However, since the Kratom powder and Kratom strains are new in the market, it is understandable that there is not that much specific information about  red maeng da kratom  from bulk kratom whatsoever available on the internet. However, several customers vastly use Kratom products because of their potency. But, it is always advisable to take Maeng da Kratom powder or Maeng da Kratom strains after consulting prescription medications professionals. Here, we will discuss some essential tips for selecting a high-quality Red Maeng da Kratom vendor for your needs. What Is Red Maeng Da Kratom Powder? Red Maeng da Kratom powder  is one of the popular Kratom strains that originated in...

Is Kratom an Opiate? Kratom Alkaloids and Effects

Image
  Concentration percentages given come from different studies of alkaloid concentrations in Mitragyna speciosa ( Kratom ) leaf. Some of the alkaloids given in this list still need to be studied more specifically in order to determine their potential activity. Mitragyna speciosa (kratom) Alkaloids Mitragynine: Indole alkaloid. Analgesic, antitussive, antidiarrheal, adrenergic, antimalarial, possible psychedelic (5-HT2A) antagonist. Mitragynine is the primary alkaloid in kratom, and is believed to be responsible for the majority of its effects. Roughly 66% of total alkaloid content found in Kratom leaf. Paynantheine: Indole alkaloid. Appears to be a smooth muscle relaxer, but there is limited research available and more needs to be done. 8.6% to 9% of total alkaloid contents in Kratom leaf. Second most abundant alkaloid. Mitraphylline: Oxindole alkaloid. Vasodilator, antihypertensive, muscle relaxer, diuretic, antiamnesic, anti-leukemic, possible immunostimulant. < 1%" of total a...

Paid Kratom User Study - National Institute of Health

Image
Use kratom regularly? You could qualify for a fully remote research study at NIDA. Complete the study on your smartphone Up to $170 provided for participation Make an impact on kratom science. See If you qualify about the KEMA Study. About The KEMA Study NIH is conducting a new study on kratom entitled “Real-world momentary assessment of kratom use accompanied by product assays: A natural history study toward an interdisciplinary characterization of kratom use and pharmacology”! That is a long name, so we typically refer to it as our Kratom Ecological Momentary Assessment (KEMA) study. Ecological momentary assessment is a method for collecting information from study participants in real time, in the moment, wherever they are. This is done using a secure app on a smartphone. This way, we can understand where, when, how, and why kratom is being used in people’s everyday lives. This Research Study is about kratom use in people’s everyday lives. Our goals are to understand krat...

Kratom Scientists Pen Letter Questioning Case Report Review

Image
   Kratom Scientists Pen Letter Questioning Case Report Review Dr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine as a solution to “kratom use disorder”. Kratom-related case reports typically originate with patients showing up to emergency rooms and physicians’ offices with symptoms. In these case reports, kratom product samples are rarely if ever tested for adulterants or contamination. The strength of the kratom product and dose levels seem to nearly always go unreported or wildly misreported (for example, the Broyan et al. review the Smith et al. letter addresses here claims the patients consumed an average of 92 grams of kratom per day). Furthermore, history or current use of other drugs is...