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Kratom Science: Latest Evidence on Safety and Regulation

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Kratom Science Update: Evidence-Based Facts The FDA has a long-standing bias against any dietary ingredient, botanical supplement, or dietary supplement that is not a chemical formulation subject to regulatory approval as a new drug. In 1994, Congress passed the Dietary Supplement Health and Education Act (DHEA) to reign in the FDA’s overregulation of dietary supplements FDA wanted banned on the premise they were highly addictive, being used to self-medicate without physician supervision, or were so poorly formulated these products posed a threat to public health requiring them to be banned. What is clearly needed is balanced regulation to ensure that kratom products purchased by consumers are pure and unadulterated, in other words meeting the same types of standards that apply to other food products, and even bottled water. Steps toward such standards were taken in states that passed their own versions of kratom consumer protection act laws. Ultimately, the Food and Drug Administratio...

Florida lawmakers look to regulate Kratom

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 JACKSONVILLE, Fla. — Florida lawmakers are looking to regulate a popular herbal supplement. It’s called Kratom and it’s used by some to treat pain and even help opiate users kick their addictions. Kratom is a tropical tree native to Southeast Asia, The main active ingredients in kratom are mitragynine and 7-hydroxymitragynine, which are found in the plant's leaves. These compounds interact with opioid receptors in the brain, producing a range of effects including pain relief, pleasure, and increased energy. Kratom has been used for centuries in traditional medicine, but its safety and effectiveness have been the subject of much debate. Some people use kratom to self-treat opioid addiction or to manage chronic pain. However, there is limited scientific research on the potential risks and benefits of using kratom, and it has not been approved for medical use by the US Food and Drug Administration (FDA), but its users testify it has its benefits. ( Related:   Kratom State Legali...

G Protein-biased kratom-alkaloids as potential treatments

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 G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder Background and Purpose Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self-medication and may be less dangerous than typical opioids because of the stronger preference of kratom alkaloids to induce receptor interaction with G proteins over β-arrestin proteins. The study hypothesizes that kratom (alkaloids) can also reduce alcohol intake. #science #research #kratomresearch #kratomstudy #alkaloids #proteins https://kratomlords.com/kratom-research/protein-biased-kratom-alkaloids-potential-treatments/ G Protein-biased kratom-alkaloids as potential treatments Abstract Background and Purpose Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self-medic...