Is Kratom an Opiate? Kratom Alkaloids and Effects
Concentration percentages given come from different studies of alkaloid concentrations in Mitragyna speciosa ( Kratom ) leaf. Some of the alkaloids given in this list still need to be studied more specifically in order to determine their potential activity. Mitragyna speciosa (kratom) Alkaloids Mitragynine: Indole alkaloid. Analgesic, antitussive, antidiarrheal, adrenergic, antimalarial, possible psychedelic (5-HT2A) antagonist. Mitragynine is the primary alkaloid in kratom, and is believed to be responsible for the majority of its effects. Roughly 66% of total alkaloid content found in Kratom leaf. Paynantheine: Indole alkaloid. Appears to be a smooth muscle relaxer, but there is limited research available and more needs to be done. 8.6% to 9% of total alkaloid contents in Kratom leaf. Second most abundant alkaloid. Mitraphylline: Oxindole alkaloid. Vasodilator, antihypertensive, muscle relaxer, diuretic, antiamnesic, anti-leukemic, possible immunostimulant. < 1%" of total a...